Optical adherence tomography (OCT) is a noninvasive imaging acclimation that has become analytical for assay and administration of ocular anatomy due to its adeptness to accomplish high-resolution, depth-resolved images of the retina, optic nerve, and antecedent segment.1 Intraoperative OCT enables high-resolution decision of intraocular capacity that cannot be visualized through the microscope abandoned and may be advantageous to plan surgery, clue surgical maneuvers, appraise outcomes, and potentially appulse surgical decision-making.2
Researchers from Duke University were the aboriginal to authenticate a microscope-integrated intraoperative OCT assay system, which activated a spectral-domain OCT (SD-OCT) accessory absorbed in the beyond amplitude amid the surgeon's eyepiece and microscope cold in a bartering surgical microscope.3 Researchers from Cleveland Clinic developed an bigger microscope-integrated SD-OCT arrangement with a heads-up-display.4 Bartering manufacturers accept back developed U.S. Food and Drug Administration-approved camera anchorage modules5,6 and absolutely chip intraoperative OCT systems.8–10 However, the antecedent declared systems accept activated SD-OCT, which has bound imaging acceleration and arresting roll-off with depth. Recently, the Duke University accumulation developed a 1,040 nm wavelength, 100 kHz A-scan bulk swept-source OCT (SS-OCT) chip intraoperative system.11 This accumulation additionally appear an intraoperative OCT apparatus able of capturing and apprehension three-dimensional (3-D) OCT abstracts in real-time.12,13
Most studies appliance intraoperative OCT accessories accept chip the OCT scanner afore the microscope objective. However, this can actualize optical aberrations and accident of OCT arresting because microscope eyes are about advised to address arresting wavelengths. To advance a modular adapter with bigger OCT angel quality, the OCT scanner can be chip afterwards the microscope objective. This post-objective scanning was ahead accustomed by coupling a bartering 100 Hz A-scan bulk time-domain OCT arrangement through a dichroic mirror placed afterwards the microscope objective.14 Although post-objective scanning has the disadvantage of abbreviation alive distance, it is modular and can accommodate with a avant-garde ambit of microscopes.
We developed and accustomed a ancestor ultrahigh-speed 400 kHz SS-OCT microscope adapter chip afterwards the objective. Bargain OCT arresting accident from appliance a post-objective adapter and custom coated fundus lenses can
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