March 6, 2018
Lenses are no best all-important for some microscopes, according to Rice University engineers developing FlatScope, a attenuate beaming microscope whose abilities affiance to beat those of old-school devices.
A cardboard in Science Advances by Rice engineers Ashok Veeraraghavan, Jacob Robinson, Richard Baraniuk and their labs describes a wide-field microscope thinner than a acclaim card, baby abundant to sit on a fingertip and able of micrometer resolution over a aggregate of several cubic millimeters.
FlatScope eliminates the tradeoff that hinders acceptable microscopes in which arrays of lenses can either accumulate beneath ablaze from a ample acreage of appearance or accumulate added ablaze from a abate field.
The Rice aggregation began developing the accessory as allotment of a federal action by the Defense Advanced Research Projects Agency as an implantable, high-resolution neural interface. But the device's abeyant is abundant greater. The advisers affirmation FlatScope, an beforehand on the labs' beforehand FlatCam, could be acclimated as an implantable endoscope, a large-area imager or a adjustable microscope.
"We anticipate of this as amping up FlatCam so it can breach alike bigger problems," Baraniuk said.
Traditional beaming microscopes are capital accoutrement in biology. They aces up beaming signals from particles amid into beef and tissues that are aflame with specific wavelengths of light. The address allows scientists to delving and clue biological agents with nanometer-scale resolution.
But like all acceptable microscopes, telescopes and cameras, their resolution depends on the admeasurement of their lenses, which can be ample and abundant and absolute their use in biological applications.
The Rice aggregation takes a altered approach. It uses the aforementioned charge-coupled accessory (CCD) chips begin in all cyberbanking cameras to abduction admission light, but the comparisons stop there. Like the FlatCam activity that aggressive it, FlatScope's acreage of appearance equals the admeasurement of the CCD sensor, which can be as ample or as baby as required. It's collapsed because it replaces the arrangement of lenses in a acceptable microscope with a custom amplitude mask.
This mask, which resembles a bar code, sits anon in advanced of the CCD. Ablaze that comes through the affectation and hits the sensor becomes abstracts that a computer affairs interprets to aftermath images.>
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